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Introduction: As COPD is a disease with malnutrition, catabolic process and chronic inflamation, vitamin deficiency may be seen frequently in COPD patients. We aimed to evaluate the levels of vitamin B12 and D, folic acid and homocystein in stable COPD patients, compare the results with healthy controls and determine the relationship between vitamin levels and pulmonary parameters.

Methods: There were 168 COPD patients from six pulmonology departments in Turkey, with 36 healthy controls. Pulmonary function test and St. George9s Respiratory Questionnaire (SGRQ) were performed. The levels of vitamin B12, folic acid and homocystein were measured in all subjects by immunochemical method, and vitamin D by HPLC (High-performance liquid chromatography) method.

Results: There were 152 men (90.5%) and 16 women (9.5%) with the mean age of 65.9±8.6 in our patient group. Our results revealed …