作者
Roberta Angelico, Silvia Trapani, Marco Spada, Michele Colledan, Jean de Ville de Goyet, Mauro Salizzoni, Luciano De Carlis, Enzo Andorno, Salvatore Gruttadauria, Giuseppe Maria Ettorre, Matteo Cescon, Giorgio Rossi, Andrea Risaliti, Giuseppe Tisone, Umberto Tedeschi, Marco Vivarelli, Salvatore Agnes, Paolo De Simone, Luigi Giovanni Lupo, Fabrizio Di Benedetto, Walter Santaniello, Fausto Zamboni, Vincenzo Mazzaferro, Massimo Rossi, Francesca Puoti, Stefania Camagni, Chiara Grimaldi, Enrico Gringeri, Lucia Rizzato, Alessandro Nanni Costa, Umberto Cillo
发表日期
2019/7
期刊
American Journal of Transplantation
卷号
19
期号
7
页码范围
2029-2043
简介
To implement split liver transplantation (SLT) a mandatory‐split policy has been adopted in Italy since August 2015: donors aged 18‐50 years at standard risk are offered for SLT, resulting in a left‐lateral segment (LLS) graft for children and an extended‐right graft (ERG) for adults. We aim to analyze the impact of the new mandatory‐split policy on liver transplantation (LT)‐waiting list and SLT outcomes, compared to old allocation policy. Between August 2015 and December 2016 out of 413 potentially “splittable” donors, 252 (61%) were proposed for SLT, of whom 53 (21%) donors were accepted for SLT whereas 101 (40.1%) were excluded because of donor characteristics and 98 (38.9%) for absence of suitable pediatric recipients. The SLT rate augmented from 6% to 8.4%. Children undergoing SLT increased from 49.3% to 65.8% (P = .009) and the pediatric LT‐waiting list time dropped (229 [10‐2121] vs 80 [12 …
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R Angelico, S Trapani, M Spada, M Colledan… - American Journal of Transplantation, 2019