作者
Vicente Navarro-López, Ana Ramírez-Boscá, Daniel Ramón-Vidal, Beatriz Ruzafa-Costas, Salvador Genovés-Martínez, Empar Chenoll-Cuadros, Miguel Carrión-Gutiérrez, José Horga de la Parte, David Prieto-Merino, Francisco M Codoñer-Cortés
发表日期
2018/1/1
期刊
JAMA dermatology
卷号
154
期号
1
页码范围
37-43
出版商
American Medical Association
简介
Importance
Oral intake of new probiotic formulations may improve the course of atopic dermatitis (AD) in a young population.
Objective
To determine whether a mixture of oral probiotics is safe and effective in the treatment of AD symptoms and to evaluate its influence on the use of topical steroids in a young population.
Design, Setting, and Participants
A 12-week randomized, double-blind, placebo-controlled intervention trial, from March to June 2016, at the outpatient hospital Centro Dermatológico Estético de Alicante, Alicante, Spain. Observers were blinded to patient groupings. Participants were children aged 4 to 17 years with moderate atopic dermatitis. The groups were stratified and block randomized according to sex, age, and age of onset. Patients were ineligible if they had used systemic immunosuppressive drugs in the previous 3 months or antibiotics in the previous 2 weeks or had a concomitant diagnosis …
学术搜索中的文章
V Navarro-López, A Ramírez-Boscá, D Ramón-Vidal… - JAMA dermatology, 2018