作者
Abdulazeem Abdulsalam Ibrahim Alkhidir, Martin J Holland, Wafa Ibrahim Elhag, Charlotte A Williams, Judith Breuer, Abdah Elfatih Elemam, Khalid Mohamed Khalid El Hussain, Mohammed Elfatih Hussein Ournasseir, Harry Pickering
发表日期
2019/12
期刊
Parasites & vectors
卷号
12
页码范围
1-11
出版商
BioMed Central
简介
Background
Trachoma, caused by ocular Chlamydia trachomatis, is the leading infectious cause of blindness worldwide. Sudan first reported trachoma in the 1930s and has since been consistently endemic. Ocular C. trachomatis previously isolated from trachoma patients in Sudan in 1963 was antigenically identical to an isolate from Saudi Arabia (A/SA1). No contemporary ocular C. trachomatis whole genome sequences have been reported from Sudan.
Methods
This study sequenced twenty ocular C. trachomatis isolates to improve understanding of pathogen diversity in North-East Africa and examine for genomic variation specific to Sudan, possibly related to the persistence of trachoma in surveyed communities. High quality, whole genome sequences were obtained from 12/20 isolates.
Results
All isolates were …
学术搜索中的文章
AAI Alkhidir, MJ Holland, WI Elhag, CA Williams… - Parasites & vectors, 2019