作者
Louise Sigfrid, Thomas M Drake, Ellen Pauley, Edwin C Jesudason, Piero Olliaro, Wei Shen Lim, Annelies Gillesen, Colin Berry, David J Lowe, Joanne McPeake, Nazir Lone, Daniel Munblit, Muge Cevik, Anna Casey, Peter Bannister, Clark D Russell, Lynsey Goodwin, Antonia Ho, Lance Turtle, Margaret E O'Hara, Claire Hastie, Chloe Donohue, Rebecca G Spencer, Cara Donegan, Alison Gummery, Janet Harrison, Hayley E Hardwick, Claire E Hastie, Gail Carson, Laura Merson, J Kenneth Baillie, Peter Openshaw, Ewen M Harrison, Annemarie B Docherty, Malcolm G Semple, Janet T Scott
发表日期
2021/9/1
期刊
The Lancet Regional Health–Europe
卷号
8
出版商
Elsevier
简介
Background
This study sought to establish the long-term effects of Covid-19 following hospitalisation.
Methods
327 hospitalised participants, with SARS-CoV-2 infection were recruited into a prospective multicentre cohort study at least 3 months post-discharge. The primary outcome was self-reported recovery at least ninety days after initial Covid-19 symptom onset. Secondary outcomes included new symptoms, disability (Washington group short scale), breathlessness (MRC Dyspnoea scale) and quality of life (EQ5D-5L).
Findings
55% of participants reported not feeling fully recovered. 93% reported persistent symptoms, with fatigue the most common (83%), followed by breathlessness (54%). 47% reported an increase in MRC dyspnoea scale of at least one grade. New or worse disability was reported by 24% of participants. The EQ5D-5L summary index was significantly worse following acute illness (median …
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