作者
Zahra Mohtasham Amiri, Nader Tanideh, Anahita Seddighi, Maral Mokhtari, Masood Amini, Alborz Shakouri Partovi, Amir Manafi, Seyedeh Sara Hashemi, Davood Mehrabani
发表日期
2017/9
期刊
World journal of plastic surgery
卷号
6
期号
3
页码范围
313
出版商
Iran Society of Plastic, Reconstructive and Aesthetic Surgeons
简介
BACKGROUND
Burn is the most devastating condition in emergency medicine leading to chronic disabilities. This study aimed to compare the effect of Lithospermum officinale, silver sulfadiazine and alpha ointments on healing of burn wounds in rat.
METHODS
Ninety-five rats were divided into 5 groups. Group 1 just underwent burn injury, and groups 2-5 received alpha ointment, silver sulfadiazine (SSD), gel base and L. officinale extract, respectively. A hot plate was used for induction of a standard 3 rd degree burn wound. Burn wounds were macroscopically and microscopically evaluated on days 7 th, 14 th and 21 st after burn induction.
RESULTS
A decrease in the number of inflammatory cells was noted when L. officinale and SSD were applied while the most inflammatory response was seen after administration of alpha ointment. The number of macrophages alone decreased after burn injury, while the …
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ZM Amiri, N Tanideh, A Seddighi, M Mokhtari, M Amini… - World journal of plastic surgery, 2017