作者
Sébastien Czernichow, A‐P Kengne, Emmanuel Stamatakis, Mark Hamer, G David Batty
发表日期
2011/9
来源
Obesity reviews
卷号
12
期号
9
页码范围
680-687
出版商
Blackwell Publishing Ltd
简介
Few studies have examined both the relative magnitude of association and the discriminative capability of multiple indicators of obesity with cardiovascular disease (CVD) mortality risk. We conducted an individual‐participant meta‐analysis of nine cohort studies of men and women drawn from the British general population resulting in sample of 82 864 individuals. Body mass index (BMI), waist circumference (WC) and waist‐to‐hip ratio (WHR) were measured directly. There were 6641 deaths (1998 CVD) during a mean of 8.1 years of follow‐up. After adjustment, a one SD higher in WHR and WC was related to a higher risk of CVD mortality (hazard ratio [95% CI]): 1.15 (1.05–1.25) and 1.15 (1.04–1.27), respectively. The risk of CVD mortality also increased linearly across quintiles of both these abdominal obesity markers with a 66% increased risk in the highest quintile of WHR. In age‐ and sex‐adjusted models …
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S Czernichow, AP Kengne, E Stamatakis, M Hamer… - Obesity reviews, 2011