作者
Jennifer R Charlton, Louis Boohaker, David Askenazi, Patrick D Brophy, Carl D’Angio, Mamta Fuloria, Jason Gien, Russell Griffin, Sangeeta Hingorani, Susan Ingraham, Ayesa Mian, Robin K Ohls, Shantanu Rastogi, Christopher J Rhee, Mary Revenis, Subrata Sarkar, Alexandra Smith, Michelle Starr, Alison L Kent
发表日期
2019/2/1
期刊
Clinical journal of the American Society of Nephrology
卷号
14
期号
2
页码范围
184-195
出版商
LWW
简介
Results
Twenty-one percent (449 of 2110) experienced early AKI. Early AKI was associated with higher risk of death (adjusted odds ratio, 2.8; 95% confidence interval, 1.7 to 4.7) and longer duration of hospitalization (parameter estimate: 7.3 days 95% confidence interval, 4.7 to 10.0), adjusting for neonatal and maternal factors along with medication exposures. Factors associated with a higher risk of AKI included: outborn delivery; resuscitation with epinephrine; admission diagnosis of hyperbilirubinemia, inborn errors of metabolism, or surgical need; frequent kidney function surveillance; and admission to a children’s hospital. Those factors that were associated with a lower risk included multiple gestations, cesarean section, and exposures to antimicrobials, methylxanthines, diuretics, and vasopressors. Risk factors varied by gestational age strata.
Conclusions
AKI in the first postnatal week is common and associated …
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JR Charlton, L Boohaker, D Askenazi, PD Brophy… - Clinical journal of the American Society of Nephrology, 2019