作者
Mohamad Teimourian, Zeinab Jafaraian, Seyed-Reza Hosseini, Mahsa Rahmani, Mogjan Bagherzadeh, Azin Aghamajidi, Ali Bijani, Hajighorban Nooreddini, Amrollah Mostafazadeh
发表日期
2016
期刊
Caspian Journal of Internal Medicine
卷号
7
期号
4
页码范围
283
出版商
Babol University of Medical Sciences
简介
Background:
In this study, we determined the serum levels of IL-17A and IL-10 in context with 1, 2 dihydroxy vitamin D3, parathormone and Ca 2+/Pi ions to investigate their pathological or protective roles respectively in bone metabolism.
Methods:
The bone mineral density (BMD) was determined for 1203 participants using energy X-ray absorptiometry. Subjects with a history of diseases and using bone metabolism medications were excluded and finally serum IL-10 was measured in 82 osteoporotic and 74 healthy individuals (mean age±SD of 71.04±6.9 and 68.58±6.9 respectively). Also, the serum level of IL-17A was assessed in 42 osteoporotic and 39 non-osteoporotic subjects (mean age±SD of 69.40±6.7 and 70.77±7.1, respectively). Serum levels of 1, 25-dihydroxyvitamin D3, Ca 2+/Pi ions and parathormone were extracted from AHAP cohort data bank.
Results:
IL-17A was detectable in 7.42 (16.67 …
引用总数
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