作者
Frits HM van Osch, Jelle Vlaanderen, Sylvia HJ Jochems, Cristina Bosetti, Jerry Polesel, Stefano Porru, Angela Carta, Klaus Golka, Xuejuan Jiang, Mariana C Stern, Wei-De Zhong, Eliane Kellen, Hermann Pohlabeln, Li Tang, James Marshall, Gunnar Steineck, Margaret R Karagas, Kenneth C Johnson, Zuo-Feng Zhang, Jack A Taylor, Carlo La Vecchia, Richard T Bryan, Frederik J van Schooten, Anke Wesselius, Maurice P Zeegers
发表日期
2019/5/1
期刊
Epidemiology
卷号
30
期号
3
页码范围
458-465
出版商
LWW
简介
Background:
Few studies have modeled smoking histories by combining smoking intensity and duration to show what profile of smoking behavior is associated with highest risk of bladder cancer. This study aims to provide insight into the association between smoking exposure history and bladder cancer risk by modeling both smoking intensity and duration in a pooled analysis.
Methods:
We used data from 15 case–control studies included in the bladder cancer epidemiology and nutritional determinants study, including a total of 6,874 cases and 17,727 controls. To jointly interpret the effects of intensity and duration of smoking, we modeled excess odds ratios per pack–year by intensity continuously to estimate the risk difference between smokers with long duration/low intensity and short duration/high intensity.
Results:
The pattern observed from the pooled excess odds ratios model indicated that for a fixed number of …
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FHM van Osch, J Vlaanderen, SHJ Jochems, C Bosetti… - Epidemiology, 2019