作者
Matthew D Neal, Ernest E Moore, Mark Walsh, Scott Thomas, Rachael A Callcut, Lucy Z Kornblith, Martin Schreiber, Akpofure Peter Ekeh, Adam J Singer, Lawrence Lottenberg, Michael Foreman, Susan Evans, Robert D Winfield, Michael D Goodman, Carl Freeman, David Milia, Noelle Saillant, Jan Hartmann, Hardean E Achneck
发表日期
2020/2/1
期刊
Journal of Trauma and Acute Care Surgery
卷号
88
期号
2
页码范围
279-285
出版商
LWW
简介
BACKGROUND
Trauma-induced coagulopathy is a major driver of mortality following severe injury. Viscoelastic goal-directed resuscitation can reduce mortality after injury. The TEG 5000 system is widely used for viscoelastic testing. However, the TEG 6s system incorporates newer technology, with encouraging results in cardiovascular interventions. The purpose of this study was to validate the TEG 6s system for use in trauma patients.
METHODS
Multicenter noninvasive observational study for method comparison conducted at 12 US Levels I and II trauma centers. Agreement between the TEG 6s and TEG 5000 systems was examined using citrated kaolin reaction time (CK. R), citrated functional fibrinogen maximum amplitude (CFF. MA), citrated kaolin percent clot lysis at 30 minutes (CK. LY30), citrated RapidTEG maximum amplitude (CRT. MA), and citrated kaolin maximum amplitude (CK. MA) parameters in …
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MD Neal, EE Moore, M Walsh, S Thomas, RA Callcut… - Journal of Trauma and Acute Care Surgery, 2020