作者
Liang Liu, Yali Jia, Hana L Takusagawa, Alex D Pechauer, Beth Edmunds, Lorinna Lombardi, Ellen Davis, John C Morrison, David Huang
发表日期
2015/9/1
期刊
JAMA ophthalmology
卷号
133
期号
9
页码范围
1045-1052
出版商
American Medical Association
简介
Importance
Vascular factors may have important roles in the pathophysiology of glaucoma. A practical method for the clinical evaluation of ocular perfusion is needed to improve glaucoma management.
Objective
To detect peripapillary retinal perfusion in glaucomatous eyes compared with normal eyes using optical coherence tomography (OCT) angiography.
Design, Setting, and Participants
Prospective observational study performed from July 24, 2013, to April 17, 2014. Participants were recruited and tested at Casey Eye Institute, Oregon Health & Science University. In total, 12 glaucomatous eyes and 12 age-matched normal eyes were analyzed. The optic disc region was imaged twice using a 3 × 3-mm scan by a 70-kHz, 840-nm-wavelength spectral OCT system. The split-spectrum amplitude-decorrelation angiography algorithm was used. Peripapillary flow index was calculated as the mean decorrelation value …
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L Liu, Y Jia, HL Takusagawa, AD Pechauer… - JAMA ophthalmology, 2015