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To assess corneal anatomic changes after LASIK with a high-speed corneal and anterior segment optical coherence tomography (CAS-OCT) system.

Cross-sectional observational study.

Fifty-one eyes of 26 healthy persons undergoing LASIK.

The CAS-OCT prototype operated at a 1.3-μm wavelength and 2000 axial scans/second. The corneas were scanned with a flap profile pattern (horizontal line, 512 axial scans) and a flap map pattern (4 radials, 256 axial scans each). Both patterns are 8 mm long and are centered on the corneal vertex. LASIK flaps were created using either a mechanical microkeratome (Hansatome; Bausch & Lomb, Inc., Rochester, NY) or a femtosecond laser (Pulsion; IntraLase Corp., Irvine, CA). Intraoperative pachymetry was performed using a 50-MHz ultrasound probe. Three OCT scans were obtained on preoperative and post-LASIK visits …