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Little information is available on the relationship between cervical sagittal alignment and health-related quality of life (HRQOL) in ankylosing spondylitis (AS) patients. The aim of this study was to identify relationships between cervical sagittal alignment and HRQOL in AS.

The study and control groups comprised 102 AS patients (15 women and 87 men) and age- and sex-matched 50 controls, respectively. All underwent anteroposterior and lateral radiographs and completed clinical questionnaires. The radiographic parameters examined were C2–C7 lordosis, C2–C7 sagittal vertical axis (SVA), T1 slope and T1 slope minus C2–C7 lordosis (TS-CL). A visual analogue scale (VAS 0–10) score for neck pain, the neck disability index (NDI), neck pain and disability (NPAD) scale and bath ankylosing spondylitis disease activity index (BASDAI …