作者
Miklos Argyelan, Zhi-De Deng, Olga Therese Ousdal, Leif Oltedal, Brian Angulo, Mate Baradits, Andrew J Spitzberg, Ute Kessler, Alexander Sartorius, Annemiek Dols, Katherine L Narr, Randall Espinoza, Jeroen A van Waarde, Indira Tendolkar, Philip van Eijndhoven, Guido A van Wingen, Akihiro Takamiya, Taishiro Kishimoto, Martin B Jorgensen, Anders Jorgensen, Olaf B Paulson, Antoine Yrondi, Patrice Péran, Carles Soriano-Mas, Narcis Cardoner, Marta Cano, Linda van Diermen, Didier Schrijvers, Jean-Baptiste Belge, Louise Emsell, Filip Bouckaert, Mathieu Vandenbulcke, Maximilian Kiebs, René Hurlemann, Peter CR Mulders, Ronny Redlich, Udo Dannlowski, Erhan Kavakbasi, Michael D Kritzer, Kristen K Ellard, Joan A Camprodon, Georgios Petrides, Anil K Malhotra, Christopher C Abbott
发表日期
2023/11/20
期刊
Molecular psychiatry
页码范围
1-9
出版商
Nature Publishing Group UK
简介
Neurostimulation is a mainstream treatment option for major depression. Neuromodulation techniques apply repetitive magnetic or electrical stimulation to some neural target but significantly differ in their invasiveness, spatial selectivity, mechanism of action, and efficacy. Despite these differences, recent analyses of transcranial magnetic stimulation (TMS) and deep brain stimulation (DBS)-treated individuals converged on a common neural network that might have a causal role in treatment response. We set out to investigate if the neuronal underpinnings of electroconvulsive therapy (ECT) are similarly associated with this causal depression network (CDN). Our aim here is to provide a comprehensive analysis in three cohorts of patients segregated by electrode placement (N = 246 with right unilateral, 79 with bitemporal, and 61 with mixed) who underwent ECT. We conducted a data-driven, unsupervised …
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M Argyelan, ZD Deng, OT Ousdal, L Oltedal, B Angulo… - Molecular psychiatry, 2023