作者
Julienne E Bower, Patricia A Ganz, Katherine A Desmond, Coen Bernaards, Julia H Rowland, Beth E Meyerowitz, Thomas R Belin
发表日期
2006/2/15
期刊
Cancer
卷号
106
期号
4
页码范围
751-758
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
BACKGROUND
A longitudinal study was designed to evaluate the prevalence, persistence, and predictors of posttreatment fatigue in breast carcinoma survivors.
METHODS
A sample of 763 breast carcinoma survivors completed questionnaires at 1–5 and 5–10 years after diagnosis, including the RAND 36‐item Health Survey, Center for Epidemiological Studies – Depression scale (CES‐D), Breast Cancer Prevention Trial Symptom Checklist, and demographic and treatment‐related measures.
RESULTS
Approximately 34% of study participants reported significant fatigue at 5–10 years after diagnosis, which is consistent with prevalence estimates obtained at 1–5 years after diagnosis. Approximately 21% reported fatigue at both assessment points, indicating a more persistent symptom profile. Longitudinal predictors of fatigue included depression, cardiovascular problems, and type of treatment received …
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