作者
Andreas Hahn, Patrycja Stein, Christian Windischberger, Andreas Weissenbacher, Christoph Spindelegger, Ewald Moser, Siegfried Kasper, Rupert Lanzenberger
发表日期
2011/6/1
期刊
Neuroimage
卷号
56
期号
3
页码范围
881-889
出版商
Academic Press
简介
Social anxiety disorder patients suffer from excessive anxious responses in social interaction leading to avoidance behavior and social impairment. Although the amygdala has a central role in perception and processing of threatening cues, little is known about the involved networks and corresponding dysfunctions in social anxiety. Therefore, this study aims to investigate the functional connectivity network of the amygdala in patients with social anxiety disorder and to identify regions that might influence amygdalar reactivity via modulatory pathways. Ten patients with anxiety disorders (social and/or panic) and 27 healthy controls underwent a facial emotion processing task as well as 6-min functional MRI at resting state. Individual voxel-wise functional connectivity maps were calculated using the amygdala as seed region. Group comparisons were done by random-effects analysis in SPM. Patients exhibited an …
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