作者
Lauri Parkkonen, Nobuya Fujiki, Jyrki P Mäkelä
发表日期
2009/6
期刊
Human brain mapping
卷号
30
期号
6
页码范围
1772-1782
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
Auditory brainstem responses provide diagnostic value in pathologies involving the early parts of the auditory pathway. Despite that, the neural generators underlying the various components of these responses have remained unclear. Direct electrical recordings in humans are possible only in limited time periods during surgery and from small regions of the diseased brains. The evidence of the generator sites is therefore fragmented and indirect, based strongly on lesion studies and animal models. Source modeling of EEG has been limited to grand averages across multiple subjects. Here, we employed magnetoencephalography (MEG) to shed more light on the neural origins of the auditory brainstem responses (ABR) and to test whether such deep brain structures are accessible by MEG. We show that the magnetic counterparts of the electric ABRs can be measured in 30 min and that they allow localization of …
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L Parkkonen, N Fujiki, JP Mäkelä - Human brain mapping, 2009