作者
Kyung-Do Park, Jongsun Park, Junsu Ko, Byung Chul Kim, Heui-Soo Kim, Kung Ahn, Kyoung-Tag Do, Hansol Choi, Hak-Min Kim, Sanghoon Song, Sunghoon Lee, Sungwoong Jho, Hong-Sik Kong, Young Mok Yang, Byung-Hak Jhun, Chulhong Kim, Tae-Hyung Kim, Seungwoo Hwang, Jong Bhak, Hak-Kyo Lee, Byung-Wook Cho
发表日期
2012/12
期刊
BMC genomics
卷号
13
页码范围
1-8
出版商
BioMed Central
简介
Background
Thoroughbred horses are the most expensive domestic animals, and their running ability and knowledge about their muscle-related diseases are important in animal genetics. While the horse reference genome is available, there has been no large-scale functional annotation of the genome using expressed genes derived from transcriptomes.
Results
We present a large-scale analysis of whole transcriptome data. We sequenced the whole mRNA from the blood and muscle tissues of six thoroughbred horses before and after exercise. By comparing current genome annotations, we identified 32,361 unigene clusters spanning 51.83 Mb that contained 11,933 (36.87%) annotated genes. More than 60% (20,428) of the unigene clusters did not match any current equine gene model. We also identified 189,973 single nucleotide variations (SNVs …
学术搜索中的文章
KD Park, J Park, J Ko, BC Kim, HS Kim, K Ahn, KT Do… - BMC genomics, 2012
