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Cyanobacteria and their interactions with phytopathogenic fungi in soil-less potting mixes is a less explored aspect in the protected cultivation of crops, as fungal diseases often bring about serious losses. The nursery of tomato was raised with A. laxa amended /unamended soil-less substrate mixes [P:C, perlite: cocopeat (1:1); C:V, cocopeat: vermiculite (1:1); P:C:V, perlite: cocopeat: vermiculite: (1:1:1)]. Preliminary investigation of percent germination of tomato seeds in the different media with the treatments illustrated the differential influence of the media, and Anabaena laxa amended treatments showing highest values, including those challenged with F. solani. To further understand the nature of such interactions in the rhizosphere, transplantation of 30 d-old seedlings was undertaken in mesocosm experiments deploying soil-less substrate mixes (P:C, C:V, P:C:V) challenged with /without Fusarium solani or …