作者
Christian Storm, Jens Nee, Achim Jörres, Christoph Leithner, Dietrich Hasper, Christoph J Ploner
发表日期
2012/12
期刊
Scandinavian journal of trauma, resuscitation and emergency medicine
卷号
20
页码范围
1-6
出版商
BioMed Central
简介
Background
Neuron specific enolase (NSE) has repeatedly been evaluated for neurological prognostication in patients after cardiac arrest. However, it is unclear whether current guidelines for NSE cutoff levels also apply to cardiac arrest patients treated with hypothermia. Thus, we investigated the prognostic significance of absolute NSE levels and NSE kinetics in cardiac arrest patients treated with hypothermia.
Methods
In a prospective study of 35 patients resuscitated from cardiac arrest, NSE was measured daily for four days following admission. Outcome was assessed at ICU discharge using the CPC score. All patients received hypothermia treatment for 24 hours at 33°C with a surface cooling device according to current guidelines.
Results
The cutoff for absolute NSE levels in patients with unfavourable outcome …
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C Storm, J Nee, A Jörres, C Leithner, D Hasper… - Scandinavian journal of trauma, resuscitation and …, 2012