作者
Andrea Corrias, Alessandra Cassio, Giovanna Weber, Alessandro Mussa, Malgorzata Wasniewska, Anna Rapa, Roberto Gastaldi, Silvia Einaudi, Federico Baronio, Maria Cristina Vigone, Maria Francesca Messina, Milva Bal, Gianni Bona, Carlo De Sanctis
发表日期
2008/6/2
期刊
Archives of pediatrics & adolescent medicine
卷号
162
期号
6
页码范围
526-531
出版商
American Medical Association
简介
Objective
To investigate the association between juvenile autoimmune thyroiditis (JAT) and thyroid cancer in pediatric patients.
Design
We conducted a retrospective study among children and adolescents affected by JAT.
Settings
Data from 6 Italian pediatric endocrinology centers were collected.
Participants
Three hundred sixty-five children and adolescents affected by JAT diagnosed at 3.6 to 17.0 years of age.
Interventions
All patients underwent clinical examination and thyroid function test every 6 to 12 months and thyroid echography every 12 to 24 months. Fine-needle aspiration biopsy was performed in 39 patients with nodule diameter of 1 cm or larger, as well as in 4 patients with nodule diameter of less than 1 cm and echographic findings suspicious for neoplasm. Twenty-three patients underwent surgery.
Main Outcome Measures
Thyroid function, echographic pattern, nodule diameter, the presence of …
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