作者
Patricia A Woicik, Scott J Moeller, Nelly Alia-Klein, Thomas Maloney, Tanya M Lukasik, Olga Yeliosof, Gene-Jack Wang, Nora D Volkow, Rita Z Goldstein
发表日期
2009/4
期刊
Neuropsychopharmacology
卷号
34
期号
5
页码范围
1112-1122
出版商
Nature Publishing Group
简介
Individuals with current cocaine use disorders (CUD) form a heterogeneous group, making sensitive neuropsychological (NP) comparisons with healthy individuals difficult. The current study examined the effects on NP functioning of four factors that commonly vary among CUD: urine status for cocaine (positive vs negative on study day), cigarette smoking, alcohol consumption, and dysphoria. Sixty-four cocaine abusers were matched to healthy comparison subjects on gender and race; the groups also did not differ in measures of general intellectual functioning. All subjects were administered an extensive NP battery measuring attention, executive function, memory, facial and emotion recognition, and motor function. Compared with healthy control subjects, CUD exhibited performance deficits on tasks of attention, executive function, and verbal memory (within one standard deviation of controls). Although CUD with …
引用总数
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