作者
Matthew TV Chan, Chew Yin Wang, Edwin Seet, Stanley Tam, Hou Yee Lai, Eleanor FF Chew, William KK Wu, Benny CP Cheng, Carmen KM Lam, Timothy G Short, David SC Hui, Frances Chung
发表日期
2019/5/14
期刊
JAMA
卷号
321
期号
18
页码范围
1788-1798
出版商
American Medical Association
简介
Importance
Unrecognized obstructive sleep apnea increases cardiovascular risks in the general population, but whether obstructive sleep apnea poses a similar risk in the perioperative period remains uncertain.
Objectives
To determine the association between obstructive sleep apnea and 30-day risk of cardiovascular complications after major noncardiac surgery.
Design, Setting, and Participants
Prospective cohort study involving adult at-risk patients without prior diagnosis of sleep apnea and undergoing major noncardiac surgery from 8 hospitals in 5 countries between January 2012 and July 2017, with follow-up until August 2017. Postoperative monitoring included nocturnal pulse oximetry and measurement of cardiac troponin concentrations.
Exposures
Obstructive sleep apnea was classified as mild (respiratory event index [REI] 5-14.9 events/h), moderate (REI 15-30), and severe (REI >30), based on …
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