作者
Sunny Singh, Ahmed Al-Darmaki, Alexandra D Frolkis, Cynthia H Seow, Yvette Leung, Kerri L Novak, Subrata Ghosh, Bertus Eksteen, Remo Panaccione, Gilaad G Kaplan
发表日期
2015/10/1
来源
Gastroenterology
卷号
149
期号
4
页码范围
928-937
出版商
WB Saunders
简介
Background & Aims
There have been varying reports of mortality after intestinal resection for the inflammatory bowel diseases (IBDs). We performed a systematic review and meta-analysis of population-based studies to determine postoperative mortality after intestinal resection in patients with IBD.
Methods
We searched Medline, EMBASE, and PubMed, from 1990 through 2015, to identify 18 articles and 3 abstracts reporting postoperative mortality among patients with IBD. The studies included 67,057 patients with ulcerative colitis (UC) and 75,971 patients with Crohn’s disease (CD), from 15 countries. Mortality estimates stratified by emergent and elective surgeries were pooled separately for CD and UC using a random-effects model. To assess changes over time, the start year of the study was included as a continuous variable in a meta-regression model.
Results
In patients with UC, postoperative mortality was …
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S Singh, A Al-Darmaki, AD Frolkis, CH Seow, Y Leung… - Gastroenterology, 2015