作者
Maximiliaan L Notenboom, Art Schuermans, Jonathan RG Etnel, Kevin M Veen, Pieter C van de Woestijne, Filip R Rega, Willem A Helbing, Ad JJC Bogers, Johanna JM Takkenberg
发表日期
2023/9/7
来源
European Heart Journal
卷号
44
期号
34
页码范围
3231-3246
出版商
Oxford University Press
简介
Aims
To support decision-making in children undergoing aortic valve replacement (AVR), by providing a comprehensive overview of published outcomes after paediatric AVR, and microsimulation-based age-specific estimates of outcome with different valve substitutes.
Methods and results
A systematic review of published literature reporting clinical outcome after paediatric AVR (mean age <18 years) published between 1/1/1990 and 11/08/2021 was conducted. Publications reporting outcome after paediatric Ross procedure, mechanical AVR (mAVR), homograft AVR (hAVR), and/or bioprosthetic AVR were considered for inclusion. Early risks (<30d), late event rates (>30d) and time-to-event data were pooled and entered into a microsimulation model. Sixty-eight studies, of which one prospective and 67 retrospective cohort studies, were included, encompassing a total of 5259 …
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