作者
Cézane Priscila Reuter, Andréia Rosane De Moura Valim, Anelise Reis Gaya, Tássia Silvana Borges, Elisa Inês Klinger, Lia Gonçalves Possuelo, Silvia Isabel Rech Franke, Lívia Kmetzsch, Marilene Henning Vainstein, Daniel Prá, Miria Suzana Burgos
发表日期
2016/5
期刊
American journal of human biology
卷号
28
期号
3
页码范围
381-386
简介
Objectives
The aim of the present study was to evaluate the relationship between the rs9939609 fat mass and obesity‐associated (FTO) polymorphism and cardiorespiratory fitness (CRF) with overweight/obesity outcomes in youth.
Methods
This study included 420 youths, comprising 211 boys and 209 girls aged 7–17. Overweight/obesity were evaluated by body mass index (BMI), waist circumference (WC), and the percentage of fat (PF) according to two skinfold thickness measurements. Genotyping of the rs9939609 polymorphism was conducted using real‐time Polymerase Chain Reaction (PCR) utilizing TaqMan® probes, and CRF was evaluated through a 9‐minute run/walk test, categorized as fit or unfit. Logistic regression was utilized to evaluate a possible association between the polymorphism and CRF, with three obesity indicators evaluated.
Results
Individuals with the genotype risk (AA) of FTO …
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CP Reuter, A Rosane De Moura Valim, AR Gaya… - American journal of human biology, 2016