作者
François Lucia, Dimitris Visvikis, Martin Vallières, Marie-Charlotte Desseroit, Omar Miranda, Philippe Robin, Pietro Andrea Bonaffini, Joanne Alfieri, Ingrid Masson, Augustin Mervoyer, Caroline Reinhold, Olivier Pradier, Mathieu Hatt, Ulrike Schick
发表日期
2019/4/1
期刊
European journal of nuclear medicine and molecular imaging
卷号
46
页码范围
864-877
出版商
Springer Berlin Heidelberg
简介
Purpose
The aim of this study was to validate previously developed radiomics models relying on just two radiomics features from 18F-fluorodeoxyglucose positron emission tomography (PET) and magnetic resonance imaging (MRI) images for prediction of disease free survival (DFS) and locoregional control (LRC) in locally advanced cervical cancer (LACC).
Methods
Patients with LACC receiving chemoradiotherapy were enrolled in two French and one Canadian center. Pre-treatment imaging was performed for each patient. Multicentric harmonization of the two radiomics features was performed with the ComBat method. The models for DFS (using the feature from apparent diffusion coefficient (ADC) MRI) and LRC (adding one PET feature to the DFS model) were tuned using one of the French cohorts (n = 112) and applied to the other French (n …
学术搜索中的文章
F Lucia, D Visvikis, M Vallières, MC Desseroit… - European journal of nuclear medicine and molecular …, 2019