作者
Judith R Mourant, Andreas H Hielscher, Angelia A Eick, Tamara M Johnson, James P Freyer
发表日期
1998/12/25
期刊
Cancer Cytopathology: Interdisciplinary International Journal of the American Cancer Society
卷号
84
期号
6
页码范围
366-374
出版商
John Wiley & Sons, Inc.
简介
BACKGROUND
The objective of this study was to determine whether there are intrinsic differences in the light scattering properties of tumorigenic and nontumorigenic cells from a multistep carcinogenesis model.
METHODS
Wavelength‐dependent and polarization‐dependent light scattering properties of cell suspensions were measured.
RESULTS
Statistically significant differences were found between the tumorigenic and nontumorigenic cells.
CONCLUSIONS
Differences in the light scattering properties of tumorigenic and nontumorigenic cells are attributed to a change in the average size of the scattering centers on the order of a few ten of nanometers. This work is relevant to the development of noninvasive optical methods for cancer diagnosis. Cancer (Cancer Cytopathol) 1998;84:366‐374. © 1998 American Cancer Society.
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JR Mourant, AH Hielscher, AA Eick, TM Johnson… - … : Interdisciplinary International Journal of the American …, 1998