作者
Joanna A Kountanis, Christie Vahabzadeh, Samuel Bauer, Maria Muzik, Ruth Cassidy, Casey Aman, Mark MacEachern, Melissa E Bauer
发表日期
2020/5/1
期刊
Journal of clinical anesthesia
卷号
61
页码范围
109658
出版商
Elsevier
简介
Study objective
This study aims to systematically review the literature to evaluate the association between labor epidural analgesia (LEA) and postpartum depression (PPD).
Design
Meta-analysis.
Setting
Obstetric patients delivering vaginally with or without LEA in a hospital.
Interventions
This study aimed to investigate the effects of providing LEA on developing PPD.
Measurements
Pooled odds ratios (OR) and 95% confidence intervals (CI) were calculated using the random effects model.
Results
A total of 356 full text articles were reviewed. Eleven articles studying 85,928 patients met inclusion criteria. The pooled unadjusted OR 1.03 and 95% CI (0.77, 1.37) suggest that LEA is not associated with a decreased risk of developing PPD.
Conclusions
Labor epidural analgesia was not shown to confer protection against developing PPD according to this meta-analysis. Future studies are needed to explore whether other …
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JA Kountanis, C Vahabzadeh, S Bauer, M Muzik… - Journal of clinical anesthesia, 2020