作者
Joo Myung Lee, Bon‐Kwon Koo, Eun‐Seok Shin, Chang‐Wook Nam, Joon‐Hyung Doh, Xinyang Hu, Fei Ye, Shaoliang Chen, Junqing Yang, Jiyan Chen, Nobuhiro Tanaka, Hiroyoshi Yokoi, Hitoshi Matsuo, Hiroaki Takashima, Yasutsugu Shiono, Doyeon Hwang, Jonghanne Park, Kyung‐Jin Kim, Takashi Akasaka, Jianan Wang
发表日期
2017/8/22
期刊
Journal of the American Heart Association
卷号
6
期号
8
页码范围
e006071
简介
Background
Data are limited regarding outcomes of deferred lesions in patients with angiographically insignificant stenosis but low fractional flow reserve (FFR). We investigated the natural history of angiographically insignificant stenosis with low FFR among patients who underwent routine 3‐vessel FFR measurement.
Methods and Results
From December 2011 to March 2014, 1136 patients with 3298 vessels underwent routine 3‐vessel FFR measurement (3V FFR‐FRIENDS study, ClinicalTrials.gov identifier NCT01621438), and this study analyzed the 2‐year clinical outcomes of 1024 patients with 2124 lesions with angiographically insignificant stenosis (percentage of diameter stenosis <50%), in which revascularization was deferred. All lesions were classified according to FFR values, using a cutoff of 0.80 (high FFR >0.80 versus low FFR ≤0.80). The primary end point was outcome of major adverse …
学术搜索中的文章
JM Lee, BK Koo, ES Shin, CW Nam, JH Doh, X Hu… - Journal of the American Heart Association, 2017