查看文章

RESULTS: Renal IR injury significantly increased Oxidative stress index (OSI) and MDA, TOS levels and significantly decreased PON-1 actvity and TAS, NO levels in serum and liver tissue (p< 0.05). Despite that, changes in these biochemical parameters related with IR injury were diminished by 3-AB administration (p< 0.05). CONCLUSIONS: The inhibition of PARP [Poly (ADP-Ribose) Polymerase] by 3-AB showed protective effects against distant liver injury triggered by renal ischemia-reperfusion by the ameliorating effects of 3-AB on oxidative stress.