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Methods

Three hundred and eighty-one T2DM outpatients who regularly attended a Consulting Clinic in Cluj were retrospectivelly included. FLI, a surrogate steatosis biomarker based on body mass index (BMI), waist circumference (WC), triglycerides (TGL) and gammaglutamyl-transferase (GGT) was used to assess NAFLD in all patients. Anthropometric and biochemical parameters were measured. Hepatic steatosis (HS) was evaluated by ultrasonography.

Results

NAFLD-FLI (defined as FLI> 60) was correlated with HS evaluated by ultrasound (r= 0.28; p< 0.001). NAFLD-FLI was detected in 79% of T2DM. The prevalence of obesity in NAFLD-FLI patients was 80%. Of the patients with normal alanine aminotransferase (ALAT), 73.8% had NAFLD. At univariate analysis, NAFLD-FLI was correlated with age (r=− 0.14; p= 0.007), sex (r= 0.20; p< 0.001), LDL cholesterol (r= 0.12; p= 0.032), HDL cholesterol (r=− 0.13; p= 0 …