作者
Mahmoud I Nassar, El-Sayed A Aboutabl, Rania F Ahmed, Ezzel-Din A El-Khrisy, Khaled M Ibrahim, Amany A Sleem
发表日期
2010/11
期刊
Pharmacognosy research
卷号
2
期号
6
页码范围
325
出版商
Wolters Kluwer--Medknow Publications
简介
Background:
Myrtus species are characterized by the presence of phenolic acids, flavonoids, tannins, volatile oils and fatty acids. They are remedies for variety of ailments. This study therefore investigated medicinal effects of Myrtus communis L.
Methods:
Bioactivity studies of Myrtus communis L. leaves were carried out on volatile oil, 7% methanol and aqueous extracts and the isolated compounds myricetin 3-O-β-glucopyranoside, myricetin 3-O-∝–rhamnopyranoside and gallic acid.
Results:
Determination of the median lethal dose (LD 50) revealed that the volatile oil, alcoholic and aqueous extracts were practically nontoxic and highly safe as no lethality was observed. The tested materials (volatile oil, alcoholic and aqueous extracts, myricetin 3-O-β-glucopyranoside, myricetin 3-O-∝–rhamnopyranoside and gallic acid) showed significant antihyperglycemic, anti-inflammatory and antinociceptive effects as compared …
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MI Nassar, ESA Aboutabl, RF Ahmed, EDA El-Khrisy… - Pharmacognosy research, 2010