作者
Weibo Le, Cai-Hong Zeng, Zhangsuo Liu, Dong Liu, Qing Yang, Rui-Xia Lin, Zheng-Kun Xia, Zhong-Min Fan, Guanghua Zhu, Ying Wu, Hong Xu, Yihui Zhai, Ying Ding, Xiaoqing Yang, Shaoshan Liang, Hao Chen, Feng Xu, Qian Huang, Hongbing Shen, Jianming Wang, Agnes B Fogo, Zhi-Hong Liu
发表日期
2012/12
期刊
BMC nephrology
卷号
13
页码范围
1-8
出版商
BioMed Central
简介
Background
The Oxford classification of IgA nephropathy (IgAN) provides a useful tool for prediction of renal prognosis. However, the application of this classification in children with IgAN needs validation in different patient populations.
Methods
A total of 218 children with IgAN from 7 renal centers in China were enrolled. The inclusion criteria was similar to the original Oxford study.
Results
There were 98 patients (45%) with mesangial proliferation (M1), 51 patients (23%) with endocapillary proliferation (E1), 136 patients (62%) with segmental sclerosis/adhesion lesion (S1), 13 patients (6%) with moderate tubulointerstitial fibrosis (T1 26-50% of cortex scarred), and only 2 patients (1%) with severe tubulointerstitial fibrosis (T2, >50% of cortex scarred). During a median follow-up duration of 56 months, 24 children (12.4 …
学术搜索中的文章
W Le, CH Zeng, Z Liu, D Liu, Q Yang, RX Lin, ZK Xia… - BMC nephrology, 2012