作者
Carlo Alviggi, Claus Y Andersen, Klaus Buehler, Alessandro Conforti, Giuseppe De Placido, Sandro C Esteves, Robert Fischer, Daniela Galliano, Nikolaos P Polyzos, Sesh K Sunkara, Filippo M Ubaldi, Peter Humaidan
发表日期
2016/6/1
期刊
Fertility and sterility
卷号
105
期号
6
页码范围
1452-1453
出版商
Elsevier
简介
The management of patients with impaired or poor ovarian response (POR) remains a controversial and complex clinical issue. A systematic review of 47 randomized controlled trials revealed 41 different definitions of POR (1). Notably, the number of oocytes retrieved was adopted as a criterion of POR in 40% of the trials, although the threshold number differed considerably among studies (1). To standardize the definition of POR, Ferraretti et al.(2) proposed new criteria, known as the ‘‘Bologna criteria,’’based on three conditions: 1) advanced maternal age (R40 years) or any other POR risk factor; 2) a previous incident of POR; and 3) a low ovarian reserve test in terms of antimüllerian hormone (AMH) and antral follicle count (AFC). Two of these three criteria are required for a POR diagnosis. In addition, two cycles with POR after maximal stimulation are sufficient to classify a patient as a poor responder even in the …
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