作者
Ana Ferrer, Rafael Sebastián, Damián Sánchez-Quintana, Jose F Rodriguez, Eduardo J Godoy, Laura Martinez, Javier Saiz
发表日期
2015/11/2
期刊
PloS one
卷号
10
期号
11
页码范围
e0141573
出版商
Public Library of Science
简介
Atrial arrhythmias, and specifically atrial fibrillation (AF), induce rapid and irregular activation patterns that appear on the torso surface as abnormal P-waves in electrocardiograms and body surface potential maps (BSPM). In recent years both P-waves and the BSPM have been used to identify the mechanisms underlying AF, such as localizing ectopic foci or high-frequency rotors. However, the relationship between the activation of the different areas of the atria and the characteristics of the BSPM and P-wave signals are still far from being completely understood. In this work we developed a multi-scale framework, which combines a highly-detailed 3D atrial model and a torso model to study the relationship between atrial activation and surface signals in sinus rhythm. Using this multi scale model, it was revealed that the best places for recording P-waves are the frontal upper right and the frontal and rear left quadrants of the torso. Our results also suggest that only nine regions (of the twenty-one structures in which the atrial surface was divided) make a significant contribution to the BSPM and determine the main P-wave characteristics.
学术搜索中的文章
A Ferrer, R Sebastián, D Sánchez-Quintana… - PloS one, 2015