作者
Jesus Juega, Manuel Requena, Carlos Piñana, Maite Rodriguez, Jessica Camacho, Marta Vidal, Teresa Moliné, Garazi Serna, Carlos Palacio-Garcia, Marta Rubiera, Alvaro Garcia-Tornel, Noelia Rodriguez-Villatoro, David Rodriguez-Luna, Marian Muchada, Marta Olive Gadea, Federica Rizzo, Marc Rodrigo-Gisbert, Carlos Lazaro, David Hernandez, Marta de Dios Lascuevas, Francesco Diana, Laura Dorado, María Hernández-Pérez, Helena Quesada, Pere Cardona Portela, Carolina De La Torre, Santiago Ramon-y-Cajal, Alejandro Tomasello, Marc Ribo, Carlos A Molina, Jorge Pagola
发表日期
2024/5/30
期刊
Journal of NeuroInterventional Surgery
出版商
British Medical Journal Publishing Group
简介
Background
The impact of thrombolytics directed towards different thrombus components regarding site of occlusion in combination with mechanical thrombectomy (MT) to achieve endovascular complete recanalization is unclear.
Methods
Retrospective analysis of a prospective database in two stroke centers. Intracranial thrombi retrieved by MT were analyzed using hematoxylin–eosin staining for fibrin and red blood cell proportions, and CD61 immunostaining for platelets proportion in thrombus (PLTPT) assessment. Thrombi composition, baseline variables, etiology, treatment features and occlusion location were analyzed.
Results
Overall, 221 patients completed the per protocol analysis and 110 cases achieved a final expanded Thrombolysis in Cerebral Infarction (eTICI) 3 (49%) of which 70 were MT (32%) by first pass effect (FPE). Thrombi from medium distal vessel occlusions had higher PLTPT compared with …
学术搜索中的文章
J Juega, M Requena, C Piñana, M Rodriguez… - Journal of NeuroInterventional Surgery, 2024