作者
Paul N Staats, Diane Davis Davey, Benjamin L Witt, Mohiedean Ghofrani, Chengquan Zhao, Leslie G Dodd, Kelly Goodrich, Mujtaba Husain, Daniel FI Kurtycz, Donna K Russell, Rulong Z Shen, Rhona J Souers, Z Laura Tabatabai, Barbara A Crothers
发表日期
2022/3/1
期刊
Journal of the American Society of Cytopathology
卷号
11
期号
2
页码范围
102-113
出版商
Elsevier
简介
Introduction
Distinguishing between low-grade squamous intraepithelial lesions (LSIL) and high-grade squamous intraepithelial lesions (HSIL) can be difficult on certain Papanicolaou (Pap) tests, hindering interobserver concordance. We investigated the variables influencing the interpretation of LSIL versus HSIL in Pap test slides rejected from the College of American Pathologists PAP education program.
Materials and methods
Eleven cytologists, who were unaware of the reference interpretation, examined 21 Pap slides (11 submitted as LSIL and 10 as HSIL) rejected from the PAP education program and recorded the number of LSIL cells, HSIL cells, keratinized dysplastic cells, LSIL clusters with mixed HSIL cells, atypical squamous metaplasia, atypical glandular cells, the presence of inflammation or infectious organisms, and the overall interpretation (LSIL or HSIL). We evaluated the significance of these 11 …
学术搜索中的文章
PN Staats, DD Davey, BL Witt, M Ghofrani, C Zhao… - Journal of the American Society of Cytopathology, 2022