作者
F Nickel, A Studier-Fischer, B Özdemir, J Odenthal, LR Müller, S Knoedler, KF Kowalewski, I Camplisson, MM Allers, M Dietrich, K Schmidt, GA Salg, HG Kenngott, AT Billeter, I Gockel, C Sagiv, OE Hadar, J Gildenblat, L Ayala, S Seidlitz, L Maier-Hein, BP Müller-Stich
发表日期
2023/4/18
期刊
European Journal of Surgical Oncology
页码范围
106908
出版商
WB Saunders
简介
Introduction
Esophagectomy is the mainstay of esophageal cancer treatment, but anastomotic insufficiency related morbidity and mortality remain challenging for patient outcome. Therefore, the objective of this work was to optimize anastomotic technique and gastric conduit perfusion with hyperspectral imaging (HSI) for total minimally invasive esophagectomy (MIE) with linear stapled anastomosis.
Material and methods
A live porcine model (n = 58) for MIE was used with gastric conduit formation and simulation of linear stapled side-to-side esophagogastrostomy. Four main experimental groups differed in stapling length (3 vs. 6 cm) and simulation of anastomotic position on the conduit (cranial vs. caudal). Tissue oxygenation around the anastomotic simulation site was evaluated using HSI and was validated with histopathology.
Results
The tissue oxygenation (ΔStO2) after the anastomotic simulation remained …
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