作者
Catherine FÚart, CÚcilia Samieri, Virginie Rondeau, HÚlŔne Amieva, Florence Portet, Jean-Franšois Dartigues, Nikolaos Scarmeas, Pascale Barberger-Gateau
发表日期
2009/8/12
期刊
Jama
卷号
302
期号
6
页码范围
638-648
出版商
American Medical Association
简介
Context
Higher adherence to a Mediterranean-type diet is linked to lower risk for mortality and chronic diseases, but its association with cognitive decline is unclear.
Objective
To investigate the association of a Mediterranean diet with change in cognitive performance and risk for dementia in elderly French persons.
Design, Setting, and Participants
Prospective cohort study of 1410 adults (≥65 years) from Bordeaux, France, included in the Three-City cohort in 2001-2002 and reexamined at least once over 5 years. Adherence to a Mediterranean diet (scored as 0 to 9) was computed from a food frequency questionnaire and 24-hour recall.
Main Outcome Measures
Cognitive performance was assessed on 4 neuropsychological tests: the Mini-Mental State Examination (MMSE), Isaacs Set Test (IST), Benton Visual Retention Test (BVRT), and Free and Cued Selective Reminding Test (FCSRT). Incident cases of dementia (n …
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