作者
Steven C Moore, I-Min Lee, Elisabete Weiderpass, Peter T Campbell, Joshua N Sampson, Cari M Kitahara, Sarah K Keadle, Hannah Arem, Amy Berrington De Gonzalez, Patricia Hartge, Hans-Olov Adami, Cindy K Blair, Kristin B Borch, Eric Boyd, David P Check, Agnès Fournier, Neal D Freedman, Marc Gunter, Mattias Johannson, Kay-Tee Khaw, Martha S Linet, Nicola Orsini, Yikyung Park, Elio Riboli, Kim Robien, Catherine Schairer, Howard Sesso, Michael Spriggs, Roy Van Dusen, Alicja Wolk, Charles E Matthews, Alpa V Patel
发表日期
2016/6/1
期刊
JAMA internal medicine
卷号
176
期号
6
页码范围
816-825
出版商
American Medical Association
简介
Importance
Leisure-time physical activity has been associated with lower risk of heart-disease and all-cause mortality, but its association with risk of cancer is not well understood.
Objective
To determine the association of leisure-time physical activity with incidence of common types of cancer and whether associations vary by body size and/or smoking.
Design, Setting, and Participants
We pooled data from 12 prospective US and European cohorts with self-reported physical activity (baseline, 1987-2004). We used multivariable Cox regression to estimate hazard ratios (HRs) and 95% confidence intervals for associations of leisure-time physical activity with incidence of 26 types of cancer. Leisure-time physical activity levels were modeled as cohort-specific percentiles on a continuous basis and cohort-specific results were synthesized by random-effects meta-analysis. Hazard ratios for high vs low levels of activity are …
学术搜索中的文章
Association of leisure-time physical activity with risk of 26 types of cancer in 1.44 million adults
SC Moore, IM Lee, E Weiderpass, PT Campbell… - JAMA internal medicine, 2016
