作者
Jerome R Lechien, Carlos Miguel Chiesa‐Estomba, Eline Beckers, Vincent Mustin, Morgane Ducarme, Fabrice Journe, Arnaud Marchant, Lionel Jouffe, Maria Rosaria Barillari, Giovanni Cammaroto, Marta P Circiu, Stéphane Hans, Sven Saussez
发表日期
2021/8
期刊
Journal of internal medicine
卷号
290
期号
2
页码范围
451-461
简介
Objective
To investigate prevalence and recovery of olfactory dysfunction (OD) in COVID‐19 patients according to the disease severity.
Methods
From 22 March to 3 June 2020, 2581 COVID‐19 patients were identified from 18 European hospitals. Epidemiological and clinical data were extracted at baseline and within the 2‐month post‐infection.
Results
The prevalence of OD was significantly higher in mild form (85.9%) compared with moderate‐to‐critical forms (4.5–6.9%; P = 0.001). Of the 1916 patients with OD, 1363 completed the evaluations (71.1%). A total of 328 patients (24.1%) did not subjectively recover olfaction 60 days after the onset of the dysfunction. The mean duration of self‐reported OD was 21.6 ± 17.9 days. Objective olfactory evaluations identified hyposmia/anosmia in 54.7% and 36.6% of mild and moderate‐to‐critical forms, respectively (P = 0.001). At 60 days and 6 months, 15.3% and 4.7 …
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JR Lechien, CM Chiesa‐Estomba, E Beckers, V Mustin… - Journal of internal medicine, 2021