作者
Mahmoud A Sakr, Kabilan Sakthivel, Towsif Hossain, Su Ryon Shin, Sumi Siddiqua, Jaehwan Kim, Keekyoung Kim
发表日期
2022/3
来源
Journal of Biomedical Materials Research Part A
卷号
110
期号
3
页码范围
708-724
出版商
John Wiley & Sons, Inc.
简介
Gelatin methacryloyl (GelMA), a photocrosslinkable gelatin‐based hydrogel, has been immensely used for diverse applications in tissue engineering and drug delivery. Apart from its excellent functionality and versatile mechanical properties, it is also suitable for a wide range of fabrication methodologies to generate tissue constructs of desired shapes and sizes. Despite its exceptional characteristics, it is predominantly limited by its weak mechanical strength, as some tissue types naturally possess high mechanical stiffness. The use of high GelMA concentrations yields high mechanical strength, but not without the compromise in its porosity, degradability, and three‐dimensional (3D) cell attachment. Recently, GelMA has been blended with various natural and synthetic biomaterials to reinforce its physical properties to match with the tissue to be engineered. Among these, nanomaterials have been extensively used …
引用总数
学术搜索中的文章
MA Sakr, K Sakthivel, T Hossain, SR Shin, S Siddiqua… - Journal of Biomedical Materials Research Part A, 2022