作者
Andrea Palermo, Giuseppe Mangiameli, Gaia Tabacco, Filippo Longo, Claudio Pedone, Silvia Irina Briganti, Daria Maggi, Fabio Vescini, Anda Naciu, Angelo Lauria Pantano, Nicola Napoli, Silvia Angeletti, Paolo Pozzilli, Pierfilippo Crucitti, Silvia Manfrini
发表日期
2016/11/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
101
期号
11
页码范围
4039-4045
出版商
Oxford University Press
简介
Context
There are no studies evaluating teriparatide for prevention of post-thyroidectomy hypocalcemia.
Objective
Our objective was to evaluate whether teriparatide can prevent postsurgical hypocalcemia and shorten the hospitalization in subjects at high risk of hypocalcemia following thyroid surgery.
Design
This was a prospective phase II randomized open-label trial.
Setting
This trial was set on a surgical ward.
Patients
Twenty-six subjects (six males, 20 females) with intact PTH lower than10 pg/ml 4 hours after thyroidectomy were included.
Intervention
Subjects were randomized (1:1) to receive SC administration of 20 mcg of teriparatide every 12 hours until the discharge (treatment group) or to follow standard clinical care (control group).
Main Outcome Measure
Adjusted …
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