作者
Steven G Coca, Aldo J Peixoto, Amit X Garg, Harlan M Krumholz, Chirag R Parikh
发表日期
2007/11/1
来源
American Journal of Kidney Diseases
卷号
50
期号
5
页码范围
712-720
出版商
WB Saunders
简介
BACKGROUND
Recently, acute kidney injury defined by small changes in serum creatinine levels was associated with worse short-term outcomes; however, the precision and variability of this association was not fully explored.
STUDY DESIGN
Systematic review and meta-analysis.
SETTING & PARTICIPANTS
Hospitalized patients.
SELECTION CRITERIA FOR STUDIES
MEDLINE and EMBASE databases were searched for observational cohort studies and randomized controlled trials published from 1990 through February 2007 that provided information for small changes in serum creatinine levels.
PREDICTOR
Small acute changes in serum creatinine levels by absolute and percentage of changes in serum creatinine levels (lower threshold for increase in serum creatinine <0.5 mg/dL or <25%).
OUTCOME
Short-term mortality (≤30 days).
RESULTS
Compared with controls, patients with a 10% to 24% increase …
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