作者
Charles H Bombardier, Jesse R Fann, Nancy R Temkin, Peter C Esselman, Jason Barber, Sureyya S Dikmen
发表日期
2010/5/19
期刊
Jama
卷号
303
期号
19
页码范围
1938-1945
出版商
American Medical Association
简介
Context
Uncertainties exist about the rates, predictors, and outcomes of major depressive disorder (MDD) among individuals with traumatic brain injury (TBI).
Objective
To describe MDD-related rates, predictors, outcomes, and treatment during the first year after TBI.
Design
Cohort from June 2001 through March 2005 followed up by structured telephone interviews at months 1 through 6, 8, 10, and 12 (data collection ending February 2006).
Setting
Harborview Medical Center, a level I trauma center in Seattle, Washington.
Participants
Five hundred fifty-nine consecutively hospitalized adults with complicated mild to severe TBI.
Main Outcome Measures
The Patient Health Questionnaire (PHQ) depression and anxiety modules were administered at each assessment and the European Quality of Life measure was given at 12 months.
Results
Two hundred ninety-seven of 559 patients (53.1%) met criteria for MDD at least once …
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