作者
Elif Hande Ozcan Cetin, Mehmet Serkan Cetin, Kumral Çağlı, Ahmet Temizhan, Mustafa Bilal Özbay, Emek Ediboglu, Özlem Özcan Çelebi, Dursun Aras, Serkan Topaloglu, Sinan Aydogdu
发表日期
2019/2/1
期刊
Biomarkers in Medicine
卷号
13
期号
2
页码范围
69-82
出版商
Taylor & Francis
简介
Aim
We aimed to investigate the association of estimated whole blood viscosity (WBV) with hemodynamic parameters and prognosis in patients with heart failure with reduced ejection fraction.
Materials & methods
Total of 542 patients were included and followed-up for median 13 months.
Results
The WBV parameters had negative relationship with right atrium pressure and positive correlation with cardiac index. The WBV parameters were found to be independent predictors of composite end point (CEP) and all-cause mortality. Every one cP increases of WBV(h) and WBV(l) were associated with 17 and 1% reductions of CEP. In Kaplan–Meier analysis, patients with low WBV quartiles were found to have significantly more CEP.
Conclusion
Being an easily accessible and costless prognosticator, WBV seems to be a novel marker for determining prognosis and an emerging tool to individualize heart failure with …
引用总数
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