作者
Anne Yee, Huai Seng Loh, Helenna Maria bt Hisham Hashim, Chong Guan Ng
发表日期
2014/1
来源
The journal of sexual medicine
卷号
11
期号
1
页码范围
22-32
出版商
Oxford University Press
简介
Introduction
For many years, methadone has been recognized as an effective maintenance treatment for opioid dependence. However, of the many adverse events reported, sexual dysfunction is one of the most common side effects.
Aim
We conducted a meta-analysis to evaluate the prevalence of sexual dysfunction among male patients on methadone and buprenorphine treatments.
Methods
Relevant studies published from inception until December 2012 were identified by searching PubMed, OVID, and Embase. Studies were selected using prior defined criteria. Heterogeneity, publication bias, and odds ratio were assessed thoroughly.
Main Outcome Measures
To examine the prevalence and odds ratio of sexual dysfunctions among the methadone and buprenorphine groups.
Results
A total of 1,570 participants …
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