作者
Manfredi Sebastiani, A Manfredi, G Vukatana, S Moscatelli, L Riato, M Bocci, M Iudici, A Principato, S Mazzuca, P Del Medico, Rossella De Angelis, Roberto D'Amico, Roberto Vicini, Michele Colaci, Clodoveo Ferri
发表日期
2012/1/1
期刊
Annals of the rheumatic diseases
卷号
71
期号
1
页码范围
67-70
出版商
BMJ Publishing Group Ltd
简介
Introduction
The early detection of systemic sclerosis (SSc) patients at high risk of developing digital ulcers could allow preventive treatment, with a reduction of morbidity and social costs. In 2009, a quantitative score, the capillaroscopic skin ulcer risk index (CSURI), calculated according to the formula ‘D×M/N2’, was proposed, which was highly predictive of the appearance of scleroderma digital ulcers within 3 months of capillaroscopic evaluation.
Objectives
This multicentre study aims to validate the predictive value and reproducibility of CSURI in a large population of SSc patients.
Methods
CSURI was analysed in 229 unselected SSc patients by nailfold videocapillaroscopy (NVC). All patients were re-evaluated 3 months later with regard to the persistence and/or appearance of new digital ulcers.
Results
57 of 229 patients presented with digital ulcers after 3 months. The receiver operating characteristic curve …
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M Sebastiani, A Manfredi, G Vukatana, S Moscatelli… - Annals of the rheumatic diseases, 2012